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Preparation of CI‐1027 Glucuronide: Metabolite of a Remarkable Lipid‐Modulating Agent
Abstract:Abstract

The preparation of the 1β‐glucuronide of the diacid, CI‐1027, is described. The key synthetic steps are coupling of the mono‐protected acid with bromoglucuronide, deacetylation, and enzymatic hydrolysis.
Keywords:O‐acylglucuronide  enzymatic hydrolysis
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