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Novel methylation. III. Methylation of tertiary amines such as pyridine and isoquinoline with alkyl carboxylates
Authors:Tetsuji Kametani  Kazuo Kigasawa  Tetsutaro Hayasaka  Mineharu Hiiragi  Haruhide Ishimaru  Setsu Asagi
Abstract:The alkylation of tertiary amines, namely, 2-dimethylaminoethanol, triethylamine, pyridine and isoquinoline with various alkyl carboxylates was investigated. This reaction afforded the corresponding quarternary ammonium salts, e.g., methylation of 2-dimethyl-aminoethanol with methyl salicylate.
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