First Synthesis of Some New 1-Aryl-4-ethoxycarbonyl- 5-dimethylaminomethyleneamino-1,2,- 3-triazole Under Vilsmeier Conditions

Abstract

Some new 1 - aryl - 4 - ethoxycarbonyl - 5 - dimethylaminomethyleneamino-1,2,3-triazoles were first prepared from 1-aryl-4-ethoxycarbonyl-5-amino-1,2,3-triazoles and N,N-dimethylformamide in the presence of phosphorus oxychloride under mild condition in excellent yields. Their structures were characterized by IR, ¹H NMR, MS, and elemental analysis, and their inhibiting effects on various bacteria were also screened.