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HIGHLY STEREOSELECTIVE SYNTHESIS OF DIALKYL 2-ALKYLIDENE GLUTARATES |
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| Abstract: | Nucleophelic substitution of dialkyl (E)-2-bromomethylene glutarates 2 by magnesium dialkyl cuprates generated in situ provided a regio and highly stereoselective methodology for the synthesis of dialkyl 2-alkylidene glutarates 3 in good yields. |
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