REGIOSELECTIVE NITRATION OF 1-ACYL-4-METHOXYINDOLINES LEADS TO EFFICIENT SYNTHESIS OF A PHOTOLABILE l-GLUTAMATE PRECURSOR

ABSTRACT

Different nitrating reagents give different ratios of 5- and 7-nitro isomers of the title indolines. The best ratio of the 7-nitro isomer was obtained with claycop–acetic anhydride, and these conditions were particularly useful for preparation of a photolabile l-glutamate derivative.