The importance of reference materials in doping-control analysis |
| |
Authors: | Lindsey G Mackay Rymantas Kazlauskas |
| |
Institution: | (1) Laboratory of Asymmetric Synthesis, Chemistry Institute of Natural Resources, Universidad de Talca, PO Box 747, Talca, Chile;(2) Center for Bioinformatics and Molecular Simulations, Universidad de Talca, PO Box 747, Talca, Chile;(3) Science Applications International Corporation (SAIC)-Frederick, Inc., National Cancer Institute, Frederick, MD 21702, USA;(4) Department of Physics and Astronomy, University of Texas at San Antonio, One UTSA Circle, San Antonio, TX 78249, USA; |
| |
Abstract: | Polyamidoamine (PAMAM) dendrimers and water-soluble 3-mercaptopropionic acid (MPA)-capped CdSe quantum dots (QDs) were combined
to produce a new gel containing supramolecular complexes of QDs/PAMAM dendrimers. The formation of the QDs/PAMAM supramolecular
complexes was confirmed by high resolution electron microscopy and Fourier transform infrared (FTIR) analyses. Molecular dynamics
simulations corroborated the structure of the new QDs/PAMAM-based supramolecular compound. Finally, on the basis of the prominent
fluorescent properties of the supramolecular complexes, PAMAM dendrimer was functionalized with folic acid to produce a new
QDs/PAMAM-folate derivative that showed an efficient and selective performance as a marker for gastric cancer cells. |
| |
Keywords: | |
本文献已被 PubMed SpringerLink 等数据库收录! |
|