Liquid—liquid Extraction Synstem Based on Non—ionic Surfactant—salt—H2O and Mechanism of Drug Extraction |
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引用本文: | LeiLI FengLIU 等.Liquid—liquid Extraction Synstem Based on Non—ionic Surfactant—salt—H2O and Mechanism of Drug Extraction[J].中国化学快报,2002,13(4):349-350. |
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作者姓名: | LeiLI FengLIU |
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作者单位: | [1]DepartmentofChemistry,GannanTeachersCollege,Ganzhou341000 [2]CollegeofChemistryandMolecularEngineering,PekingUniversity,Beijing100871 |
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摘 要: | Extraction behavior of chlorpromazine hydrochloride (CPZ) and procaine hydrochloride (PCN) in the system described in the title was studied. Research shows that the extraction efficiency of CPZ can amount to 96% by twice extraction, while that of PCN is 77%. This system produces the distribution coefficients (KD) of 12.3 and 2.6 respectively for CPZ and PCN. Extraction mechanism is deduced according to ultraviolet and molecular fluorescence spectra variation of the drugs in the system studied.
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关 键 词: | 无离子表面活性剂 盐 液-液萃取体系 药物提取 |
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