全氟/多氟化合物分析方法的研究进展

随着全氟和多氟化合物（perfluoroalkyl and polyfluoroalkyl substances，PFASs）被列入《斯德哥尔摩公约》的持久性有机污染物名录，各国对于该类物质的关注逐步升高。该类物质在环境中的广泛检出，使得其环境行为研究不断扩展和加深。目前，针对不同类型PFASs的样品前处理方式与检测方法也在不断发展中，而从中选择最合适的前处理和分析方法是开展PFASs环境科学、管理和污染控制研究的前提。该文针对传统PFASs及其异构体、PFASs前体物和新型PFASs等的样品前处理方法、色谱-质谱分析方法进行归纳总结，认识其现状和问题，并在此基础上对其发展进行了展望。

Research progress on the analytical method of perfluoroalkyl and polyfluoroalkyl substances

With the gradual implementation of the Stockholm Convention on persistent organic pollutants (POPs), perfluoroalkyl and polyfluoroalkyl substances (PFASs) have attracted more extraordinary attentions from environmental researchers. Researches into the environmental persistence, toxicity and bioaccumulative potential of PFASs have entered a new stage of rapid development owing to their massive detection in various environmental media. Because of the regulatory limitations on legacy PFASs, their isomers and precursors, and various emerging PFASs as their substituents have been concerned by many scientists and organizations. Till date, numerous methods for the sample pretreatment and analysis of diverse PFASs have been proposed, which have distinctive advantages. Hence, appropriate choice of the analytical method is imperative for studying the environmental behavior and fate of PFASs, even for precautionary environmental management. This paper reviews the research progress on pretreatment and analytical methods, including HPLC-MS, GC-MS and HPLC-high resolution mass spectrometry (HRMS), GC-HRMS, used for the determination of legacy PFASs as well as, their isomers and precursors, and emerging PFASs. The current problems and critical areas of research that warrant further attention are also discussed herein.