Procedure for quantitative determination of effectiveness of photoinduced destruction of malignant tumors |
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| Authors: | S A Bizyuk Yu P Istomin B M Dzhagarov |
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| Institution: | (1) Institute of Molecular and Atomic Physics, National Academy of Sciences of Belarus, 70 prosp. Nezavisimosti, Minsk, 220072, Belarus;(2) N. N. Aleksandrov Scientific-Research Institute of Oncology and Medical Radiology (State Institution), Minsk, Belarus |
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| Abstract: | We have developed a procedure for analysis of the functional status of blood vessels in tumor tissues using computer-assisted
color scanning of tumor slices and also for a quantitative assessment of the effectiveness of photoinduced destruction of
tumor tissues in animal experiments. Its major advantage is direct determination of the size of the tumor necrosis zone. The
procedure has been tested in an experiment on three strains of malignant tumors with different morphologies.
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Translated from Zhurnal Prikladnoi Spektroskopii, Vol. 73, No. 4, pp. 521–524, July–August, 2006. |
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| Keywords: | photodynamic cancer therapy tumor necrosis photoinduced reactions laser radiation photosensitizer |
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