Positron Emission Intensity in the Decay of 86gY for Use in Dosimetry Studies |
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| Authors: | M Shuza Uddin Syed M Qaim Bernhard Scholten M Shamsuzzoha Basunia Lee A Bernstein Ingo Spahn Bernd Neumaier |
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| Institution: | 1.Institute of Neuroscience and Medicine, INM-5: Nuclear Chemistry, Forschungszentrum Jülich, D-52425 Jülich, Germany; (B.S.); (I.S.); (B.N.);2.Tandem Accelerator Facilities, INST, Atomic Energy Research Establishment, Savar, Dhaka 1000, Bangladesh;3.Nuclear Science Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA; (M.S.B.); (L.A.B.);4.Department of Nuclear Engineering, UC Berkeley, Berkeley, CA 94720, USA |
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| Abstract: | The β+-emitting radionuclide 86gY (t1/2 = 14.7 h) forms a matched-pair with the β−-emitting therapeutic radionuclide 90Y (t1/2 = 2.7 d) for theranostic application in medicine. This approach demands a precise knowledge of the positron emission probability of the PET nuclide which was until recently rather uncertain for 86gY. In this work, an 86gY source of high radionuclidic purity was prepared and a direct measurement of the positron emission intensity per 100 decay of the parent (hereafter “positron emission intensity”) was performed using high-resolution HPGe detector γ-ray spectroscopy. The electron capture intensity was also determined as an additional check by measuring the Kα and Kβ X-rays of energies 14.1 and 15.8 keV, respectively, using a low energy HPGe detector. From those measurements, normalized values of 27.2 ± 2.0% for β+-emission and 72.8 ± 2.0% for EC were obtained. These results are in excellent agreement with values recently reported in the literature based on a detailed decay scheme study. |
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| Keywords: | positron emission electron capture gamma-ray X-ray 86gY radionuclide matched-pair theranostic application |
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