Recent Advances in Visible-Light Photoredox Catalysis for the Thiol-Ene/Yne Reactions |
| |
| Authors: | Qian Xiao Qing-Xiao Tong Jian-Ji Zhong |
| |
| Institution: | 1.School of Chemistry and Environmental Engineering, Hanshan Normal University, Chaozhou 521041, China;2.Key Laboratory for Preparation and Application of Ordered Structural Materials of Guangdong Province, Department of Chemistry, Shantou University, Shantou 515063, China;3.The Chemistry and Chemical Engineering Laboratory of Guangdong Province, Shantou 515063, China |
| |
| Abstract: | Visible-light photoredox catalysis has been established as a popular and powerful tool for organic transformations owing to its inherent characterization of environmental friendliness and sustainability in the past decades. The thiol-ene/yne reactions, the direct hydrothiolation of alkenes/alkynes with thiols, represents one of the most efficient and atom-economic approaches for the carbon-sulfur bonds construction. In traditional methodologies, harsh conditions such as stoichiometric reagents or a specialized UV photo-apparatus were necessary suffering from various disadvantages. In particular, visible-light photoredox catalysis has also been demonstrated to be a greener and milder protocol for the thiol-ene/yne reactions in recent years. Additionally, unprecedented advancements have been achieved in this area during the past decade. In this review, we will summarize the recent advances in visible-light photoredox catalyzed thiol-ene/yne reactions from 2015 to 2021. Synthetic strategies, substrate scope, and proposed reaction pathways are mainly discussed. |
| |
| Keywords: | photoredox catalysis thiol-ene/yne reaction synthetic methodologies green chemistry |
|
|
