Voltammetric study of levomepromazine induced ionic permeability in a model lipid membrane system |
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| Authors: | Miroslav Karabaliev Valery Kochev |
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| Affiliation: | a Department of Physics and Biophysics, Faculty of Medicine, Trakia University, 11 Armeiska, Stara Zagora 6003, Bulgaria;b Department of Atomic Physics, Sofia University, “Kl.Ohridsky”, 5 J.D.Bourchier, Sofia 1164, Bulgaria |
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| Abstract: | The interaction of solid supported liquid films of lipids with levomepromazine is investigated in the present work by voltammetry. It is shown that the levomepromazine penetrates into the films, which results in a readily detectable change of the film permeability to electroactive species. In this respect, possibilities for the employment of supported lipid films as model systems in the research of biomembrane active compounds are briefly discussed. |
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| Keywords: | Solid supported thin liquid films of lipid Glassy carbon Levomepromazine Voltammetry |
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