首页 | 本学科首页   官方微博 | 高级检索  
     检索      


Iron-catalyzed [2pi + 2pi] cycloaddition of alpha,omega-dienes: the importance of redox-active supporting ligands
Authors:Bouwkamp Marco W  Bowman Amanda C  Lobkovsky Emil  Chirik Paul J
Institution:Department of Chemistry and Chemical Biology, Baker Laboratory, Cornell University, Ithaca, NY 14850, USA.
Abstract:The bis(imino)pyridine iron bis(dinitrogen) complex, (iPrPDI)Fe(N2)2 (iPrPDI = 2,6-(2,6-iPr2C6H3NCR)2C5H3N), serves as an efficient precursor for the catalytic 2pi + 2pi] cycloaddition of alpha,omega-dienes to yield the corresponding bicycles. For amine substrates, the rate of catalytic turnover increases with the size of the nitrogen substituents, demonstrating competing heterocycle coordination and product inhibition. In one case, a bis(imino)pyridine iron azobicycloheptane product was characterized by X-ray diffraction. Preliminary mechanistic studies highlight the importance of the redox activity of the bis(imino)pyridine ligand to maintain the ferrous oxidation state throughout the catalytic cycle.
Keywords:
本文献已被 PubMed 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号