WAVELENGTH DEPENDENCE OF SINGLET OXYGEN MECHANISM IN ACRIDINE ORANGE-SENSITIZED PHOTODYNAMIC ACTION IN YEAST CELLS: EXPERIMENTS WITH 470 NM |
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| Authors: | Katsumi Kobayashi Takshi Ito |
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| Affiliation: | Institute of Physics, College of General Education, University of Tokyo, Komaba, Meguroku, Tokyo 153, Japan |
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| Abstract: | Abstract— The singlet oxygen mechanism was evaluated in terms of acridine orange-sensitized induction of gene conversion in Saccharomyces at 470 nm and by using a concentration dependent protective action of added N;. The singlet oxygen mechanism accounted for 96% of the total photodynamic efTect. This value is to be contrasted with 76% previously observed for 510 nm illumination. |
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