Design,synthesis,in vitro evaluation of tetrahydropyrimidine-isatin hybrids as potential antibacterial,antifungal and anti-tubercular agents |
| |
| Authors: | Tarunkumar Nanjibhai Akhaja Jignesh Priyakant Raval |
| |
| Institution: | Department of Pharmaceutical Chemistry, Ashok & Rita Patel Institute of Integrated Study and Research in Biotechnology and Allied Sciences (ARIBAS), New Vallabh Vidyanagar-388121, Gujarat, India |
| |
| Abstract: | A series of 5-substitued-3-(5-(4-(furan-2-yl)-6-methyl-2-oxo/thioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-1,3,4-thiadiazol-2- ylimino)indolin-2-one derivatives were synthesized,characterized and were screened for anti-bacterial,anti-fungal and antitubercular activity. |
| |
| Keywords: | Tetrahydropyrimidines Isatin 1 3-Dihydro-2H-indol-2-ones Biginelli reaction CaCl2 catalyst In vitro antituberculer activity Antibacterial and antifungal activity |
| 本文献已被 CNKI ScienceDirect 等数据库收录！ |
| 点击此处可从《中国化学快报》浏览原始摘要信息 |
| 点击此处可从《中国化学快报》下载免费的PDF全文 |
|
