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4-Methoxy-3-methylgoniothalamin from marine-derived fungi of the genus Penicillium |
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| Authors: | Smetanina O. F. Yurchenko A. N. Kalinovsky A. I. Pushilin M. A. Slinkina N. N. Yurchenko E. A. Afiyatullov Sh. Sh. |
| Affiliation: | 1.Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, 159 prosp. 100-letiya Vladivostoka, 690022, Vladivostok, Russian Federation ;2.Far Eastern Federal University, 8 ul. Sukhanova, 690000, Vladivostok, Russian Federation ;3.Institute of Chemistry, Far Eastern Branch of the Russian Academy of Sciences, 159 prosp. 100-letiya Vladivostoka, 690022, Vladivostok, Russian Federation ; |
| Abstract: | The new styrylpyrone derivative, viz. 4-methoxy-3-methylgoniothalamin (1), and the known compound sulochrin were isolated from the marine-derived fungi Penicillium glabrum and P. implicatum. The structure of compound 1 was determined by X-ray diffraction, 2D NMR spectroscopy, and high-resolution mass spectrometry. It was shown for the first time that sulochrin increases expression of the protein Hsp70. |
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