Carcinosarcoma of the uterus: radiologic-pathologic correlations with magnetic resonance imaging including diffusion-weighted imaging |
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Authors: | Kato Hiroki Kanematsu Masayuki Furui Tatsuro Imai Atsushi Hirose Yoshinobu Kondo Hiroshi Goshima Satoshi Tsuge Yusuke |
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Affiliation: | aDepartment of Radiology, Gifu University School of Medicine, 1-1 Yanagido, Gifu 501-1194, Japan;bHigh-level Imaging Diagnosis Center, Gifu University Hospital, Gifu, Japan;cDepartment of Obstetrics and Gynecology, Gifu University School of Medicine, Gifu, Japan;dDepartment of Pathology, Gifu University School of Medicine, Gifu, Japan |
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Abstract: | The authors describe the MRI findings, including diffusion-weighted imaging findings, of histopathologically proven uterine carcinosarcoma in four postmenopausal women. In three of four patients, diffusion-weighted images clearly revealed hypointense areas corresponding to hypocellular regions caused by intratumoral necrosis, and apparent diffusion coefficient (ADC) mapping images indicated that necrotic areas had high ADC values. In the remaining patient, diffusion-weighted and ADC mapping images clearly distinguished components of adenocarcinoma from sarcoma. In all patients, diffusion-weighted and ADC mapping images precisely reflected histopathological findings. Diffusion-weighted images were found to demonstrate complicated tissue components in carcinosarcomas of the uterus, and thus, which may be useful for the diagnosis of this disease. |
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Keywords: | Carcinosarcoma Uterus Magnetic resonance (MR) Diffusion-weighted images |
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