Synthesis ofω-substituted 3-alkylorotic acids |
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| Authors: | A Ya Berlin I A Korbukh |
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| Institution: | (1) Institute of Experimental and Clinical Oncology, Academy of Medical Sciences of the USSR, Moscow |
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| Abstract: | 3-( -Phthalimidoalkyl)-5-carbethoxymethylenehydantoins were synthesized by the reaction of-phthalimidoalkylureas with ethyl oxalacetate and then converted to 3-(-aminoalkyl)orotic acids. Condensation of the latter with 6-chloropurine yielded 3--(6-purinylamino)alkyljorotic acids.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 397–399, March, 1971. |
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