| 主要抗病候选基因在猪抗病育种中的研究进展 |
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| 引用本文： | 李晓丽,何万领,董淑丽,邓昌彦.主要抗病候选基因在猪抗病育种中的研究进展[J].河南科技大学学报(自然科学版),2006,27(5):65-68. |
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| 作者姓名： | 李晓丽 何万领 董淑丽 邓昌彦 |
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| 作者单位： | 1. 河南科技大学,动物科技学院,河南,洛阳,471003
2. 华中农业大学,动物科技学院猪遗传育种重点开放实验室,湖北,武汉,430070 |
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| 基金项目： | 国家863项目(2001—AA—243031) |
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| 摘 要： | 寻找与动物生理、生化、病理、连锁等方面有关的基因作为候选基因,分析候选基因的标记等位基因频率差异、标记等位基因的有无在抗性和易感性2个群体中的差异,从而间接地进行抗病育种,是一种有效的方法。本文对影响动物抗病力的天然抗性巨噬结合蛋白基因、干扰素基因、肠毒素型大肠杆菌K88受体基因、主要组织相容性复合体基因家族、MX抗病毒蛋白基因的国内外研究进行概述。
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| 关 键 词： | 猪 候选基因 抗病育种 |
| 文章编号： | 1672-6871（2006）05-0065-04 |
| 收稿时间： | 2006-01-15 |
| 修稿时间： | 2006年1月15日 |
Advance of Major Anti-disease Candidate Genes in Pig Disease-Resistant Breeding |
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| LI Xiao-Li,HE Wan-Ling,DONG Shu-Li,DENG Chang-Yan.Advance of Major Anti-disease Candidate Genes in Pig Disease-Resistant Breeding[J].Journal of Henan University of Science & Technology:Natural Science,2006,27(5):65-68. |
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| Authors: | LI Xiao-Li HE Wan-Ling DONG Shu-Li DENG Chang-Yan |
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| Institution: | LI Xiao-Li~1,HE Wan-Ling~1,DONG Shu-Li~1,DENG Chang-Yan~2 |
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| Abstract: | With the development of molecular biology and gene engineering technology,improving animal anti-disease ability and health level has been an important approach through anti-disease genetics and breeding.Genes associating with animal physiology,biochemistry,pathology and linkage are used as candidate genes.The differences between marker allele frequencies of candidate genes and marker allele genes in fastness and susceptibility are analyzed,and the research of anti-disease breeding which is carried out indirectly has become an effective approach.In this paper,the research advance of NRAMP1,INF,ETEC K88,MHC and MX genes affecting disease resistance in animals is reviewed. |
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| Keywords: | Pig Candidate genes Disease-resisitant breeding |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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