On the Novel Free Porphyrins Corallistin B,C, D,and E: Isolation from the demosponge Corallistes sp. of the Coral Sea and Reactivity of Their Nickel 55 (II) Complexes toward Formylating Reagents |
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Authors: | Michele D'Ambrosio,Antonio Guerriero,Francesco Pietra,C cile Debitus,Olivier Ribes |
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Affiliation: | Michele D'Ambrosio,Antonio Guerriero,Francesco Pietra,Cécile Debitus,Olivier Ribes |
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Abstract: | Reported here are the novel free porphyrins corallistin B, C, D, and E, isolated as methyl esters 2a , 3a , 4a , and 5a , respectively, from the sponge Corallistes sp. (Lithistida) collected at the basis of the south New Caledonian coral reef. A protocol is also established for formylation of their NiII complexes, which show a different reactivity pattern toward DMF/POCl3 from metal complexes of deuteroporphyrins. Together with corallistin A, Previously isolated as the methyl ester 1a , and the known deuteroporphyrin IX (isolated as 6a ) also present in the sponge, the new corallistins, which may be thought to derive from protoporphyrin via heme, account for an amazing 60% of the EtOh extract from the sponge. |
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