Preparation of 8-alkylaminoquinolines from 8-chloroquinolines |
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| Authors: | N N Vorozhtsov Jr N I Skrebkova |
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| Institution: | (1) Novosibirsk Institute of Organic Chemistry, Siberian Division, AS USSR, USSR |
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| Abstract: | The chlorine of 8-chloroquinoline undergoes a metathetical reaction with methylamine or ethylamine in aqueous solution under pressure in the presence of cuprous chloride, to give 8-methylaminoquinoline and 8-ethylaminoquinoline. The preparation of 8-aminoquinoline from 8-chloroauinoline is confirmed. |
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