Catalytic Aerobic Phenol Homo- and Cross-Coupling Reactions with Copper Complexes Bearing Redox-Active Guanidine Ligands |
| |
Authors: | Florian Schön Dr Elisabeth Kaifer Prof Hans-Jörg Himmel |
| |
Institution: | Anorganisch-Chemisches Institut, Ruprecht-Karls-Universität Heidelberg, Im Neuenheimer Feld 270, 69120 Heidelberg, Germany |
| |
Abstract: | Due to their large importance in synthetic chemistry, catalytic C−C coupling reactions of phenols are currently intensively studied. Herein, new copper catalysts for the C−C coupling reaction of phenols using dioxygen as a green oxidizing reagent are reported. By using redox-active guanidine ligands, the activity as well as chemoselectivity in the cross-coupling reaction of non-complementary phenols (between an electron-rich phenol and a less nucleophilic second phenol) is significantly improved. Based on the collected data for several test reactions, a reaction mechanism is proposed. |
| |
Keywords: | catalysis cross-coupling guanidines phenols redox-active ligands |
|
|