Synthesis of Chiral Labtb and Visualization of Its Enantiomeric Excess by Induced Circular Dichroism Imaging |
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Authors: | Dr Teppei Yamada Toshiki Eguchi Taro Wakiyama Dr Tetsuya Narushima Dr Hiromi Okamoto Dr Nobuo Kimizuka |
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Institution: | 1. Graduate School of Engineering, Department of Chemistry, and Biochiemistry, Kyushu University, Motooka 744, Nishi-ku, Fukuoka, 819-0395 Japan;2. PRESTO, Japan Science and Technology Agency, 4-1-8 Honcho, Kawaguchi, Saitama, 332-0012 Japan;3. Institute for Molecular Science, 38 Nishigonaka, Myodaiji, Okazaki, Aichi, 444-8585 Japan |
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Abstract: | Crystalline particles of a microporous, robust, and chiral metal–organic framework (MOF) were synthesized and their enantiomer excess (ee) was visualized for each microparticle by CD imaging. Labtb, a thermally and chemically robust MOF, was employed in this study because it shows a chiral space group. Although Labtb has been obtained as a racemic conglomerate, enantioselective synthesis of Labtb was achieved via a chiral precursor complex consisting of lanthanum and homochiral phenylalanine. Methyl orange (MO) was introduced into the micropores of chiral Labtb, which showed a strong induced CD signal for the absorption band of MO chromophores. High ee of the chiral Labtb was revealed by microscopic CD observation at the particle-level. This result provides a facile way to obtain a robust MOF that has chiral nanospace. |
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Keywords: | CD imaging chiral MOFs enantomeric excess metal–organic frameworks porous coordination polymers |
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