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Iron/copper-catalyzed C-C cross-coupling of aryl iodides with terminal alkynes
Authors:Chandra M. Rao Volla
Affiliation:Laboratoire de Glycochimie et Synthèse Asymétrique (LGSA), Swiss Federal Institute of Technology Lausanne (EPFL), Batochime, 1015 Lausanne, Switzerland
Abstract:Synergic effect of iron and copper salts as catalysts for the Sonogashira-Hagihara cross-couplings of aryl iodides with terminal alkynes is demonstrated. High yields of cross-coupled products are obtained under conditions that are smoother than those using only CuI as catalyst. Furthermore no expensive or/and toxic ligand is required.
Keywords:Sonogashira-Hagihara coupling   Iron   Copper   Synergic effect
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