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Total synthesis of (+)-lentiginosine from d-glucose
Authors:Mohammad Abrar Alam
Affiliation:Department of Chemistry, Indian Institute of Technology, Kanpur 208 016, India
Abstract:A total synthesis of (+)-lentiginosine, a potent and selective amyloglucosidase inhibitor, is reported from a d-glucose-derived epoxide in 38% overall yield. In this synthesis, ambient conditions and readily available starting materials and reagents are used.
Keywords:(+)-Lentiginosine     smallcaps"  >d-Glucose   Epoxide   Barton deoxygenation
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