First synthesis of 5-fluoro-(+)-MK7607, its 1-epimer and 6-deoxy derivative |
| |
| Authors: | João Sardinha Amelia Pilar Rauter |
| |
| Institution: | a UPMC Univ Paris 06, Institut de Chimie Moléculaire (FR 2769), Laboratoire de Chimie Organique (UMR CNRS 7611), Tours 44-45, 1er étage, C. 181, 4 place Jussieu, 75005 Paris, France
b Departamento de Química e Bioquímica, Faculdade de Ciências da Universidade de Lisboa, Edifício C8, 5 Piso, 1749-016 Lisboa, Portugal |
| |
| Abstract: | (+)-MK7607 is a patented naturally occurring unsaturated pseudo-carbasugar possessing herbicidal activity. We present herein the first synthesis of the 5-fluorinated analogue (1S, 2S, 3R, 4R)-5-fluoro-6-(hydroxymethyl)cyclohex-5-ene-1,2,3,4-tetrol as well as that of two related compounds, namely its 1-epimer and its 6-deoxy derivative. |
| |
| Keywords: | Cabasugars Fluorine Mimics Inositol |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
