One-pot synthesis of highly substituted tetrahydrofurans from activated propargyl alcohols using Bu3P |
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| Authors: | Yakambram Pedduri |
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| Affiliation: | Department of Medicinal Chemistry, School of Pharmacy, The University of Mississippi, University, MS 38677, United States |
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| Abstract: | General and robust synthesis of highly functionalized tetrahydrofuran ring was accomplished with activated propargyl alcohol and reactive Michael acceptors in the presence of catalytic Bu3P. |
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| Keywords: | Tandem conjugate addition Double Michael addition Tributylphosphine Tetrahydrofuran ring |
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