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Metal ion-induced FRET modulation in a bifluorophore system
Authors:Su Yeon Lee  Jia-Sheng Wu  Jong Seung Kim
Affiliation:a Department of Chemistry, Korea University, Seoul 136-701, Republic of Korea
b Department of Chemistry, Sookmyung Women’s University, Seoul 140-742, Republic of Korea
Abstract:A new fluorogenic sensor 1 capable of illustrating metal ion-triggered FRET changes has been synthesized. Based on the FRET changes, 1, bearing coumarin-fluorescein moieties, provides a selective sensor for Cu2+ and Hg2+ ions for experiments implemented in aqueous media with a chloride counter anion.
Keywords:FRET   Fluorescence   Heavy metal ion effect
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