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On the problem of the purity of solvents in HPTLC |
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| Authors: | J A De Schutter G Van der Weken W Van den Bossche P De Moerloose |
| Institution: | (1) Department of Pharmaceutical Chemistry and Drug Quality Control, Stae University of Gent, Harelbekestraat 72, B-9000 Gent, Belgium |
| Abstract: | Summary The influence of stabilizers (2,6-di-tert-butyl-4-methylphenol and hydroquinone) and impurities in solvents on the reproducibility of the quantitative stability-indicating determination of mebeverine hydrochloride by means of high-performance thin-layer chromatography is reported. |
| Keywords: | Thin-layer chromatography Stabilizers Solvent purity Mebeverine hydrochloride |
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