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Synthesis of 1-benzyl-3,6-diazahomoadamantane |
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| Authors: | A. I. Kuznetsov I. M. Senan R. T. Alasadi A. Kh. Shukkur T. M. Serova |
| Affiliation: | 1. Lomonosov Moscow State University of Fine Chemical Technologies, Moscow, 119571, Russia 3. University of Kerbala, Kerbala, Iraq 2. Institute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka, Russia |
| Abstract: | By condensation of 4-phenylbutan-2-one with tetramethylenediethylenetetramine 1-benzyl-3,6-diazahomoadamantan-9-one was synthesized. Further nitration of 1-benzyl-3,6-diazahomoadamantan-9-one yielded 1-(4-nitrobenzyl)-3,6-dia?ahomoadamantan-9-one. The modification of the nitro and carbonyl groups resulted in the formation of 1-benzyl-3,6-diazahomoadamantane and its derivatives with functional groups in the benzene ring and at the bridge carbon atom C9. |
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