A green and convenient approach for the synthesis of methyl 6-amino-5-cyano-4-aryl-2,4-dihydropyrano[2,3-c]pyrazole-3-carboxylates via a one-pot, multi-component reaction in water |
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| Authors: | Adeleh Moshtaghi Zonouz Issa EskandariHamid Reza Khavasi |
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| Affiliation: | a Chemistry Department, Faculty of Science, Azarbaijan Shahid Madani University, Tabriz, Iran
b Shahid Beheshti University, G.C., Evin, Tehran 1983963113, Iran |
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| Abstract: | A green and efficient one-pot, four-component synthesis of methyl 6-amino-5-cyano-4-aryl-2,4-dihydropyrano[2,3-c]pyrazole-3-carboxylates in water is described. The method is catalyst-free, atom-economical, and does not involve tedious work-up or purification affording the target compounds in good yields. |
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| Keywords: | Pyrano[2,3-c]pyrazole Multi-component reaction Tandem reaction Green synthesis |
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