1,6-dihydro-3(2H)-pyridinones as synthetic intermediates. A novel total synthesis of (±)-ibogamine and (±)-epiibogamine |
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Authors: | Takeshi Imanishi Noriyuki Yagi Hiroaki Shin Miyoji Hanaoka |
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Institution: | Faculty of Pharmaceutical Sciences, Kanazawa University Takara-machi, Kanazawa 920, Japan |
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Abstract: | A new synthesis of (±)-ibogamine () and (±)-epiibogamine (), involving the intramolecular Michael addition of the keto unsaturated ester (), is described. |
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