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1,6-dihydro-3(2H)-pyridinones as synthetic intermediates. A novel total synthesis of (±)-ibogamine and (±)-epiibogamine
Authors:Takeshi Imanishi  Noriyuki Yagi  Hiroaki Shin  Miyoji Hanaoka
Institution:Faculty of Pharmaceutical Sciences, Kanazawa University Takara-machi, Kanazawa 920, Japan
Abstract:A new synthesis of (±)-ibogamine (4) and (±)-epiibogamine (5), involving the intramolecular Michael addition of the keto unsaturated ester (11), is described.
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