A graphene oxide-peptide fluorescence sensor tailor-made for simple and sensitive detection of matrix metalloproteinase 2 |
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Authors: | Feng Duan Zhang Yangyang Feng Tingting Shi Wen Li Xiaohua Ma Huimin |
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Affiliation: | Beijing National Laboratory for Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China. |
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Abstract: | A graphene oxide-peptide based fluorescence sensor has been developed for matrix metalloproteinase 2 (MMP2), and its applicability has been demonstrated by monitoring the concentration of MMP2 secreted by HeLa cells, revealing that HeLa cells with a density of 5.48 × 10(5) cells per mL can produce 22 nM in cell culture media in 24 h. |
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