| Total Synthesis of the Analogue of Icogenin |
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| 作者姓名： | Shu Jie HOU Peng XU Liang ZHOU De Quan YU Ping Sheng LEI Chuan Chun ZOU |
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| 作者单位： | [1]Key Laboratory of Bioactive Substance and Resources Utilization of Chinese Herbal Medicine（Peldng Union Medical College）, Ministry of Education [2]Institute of Materia Medica, Peking Union Medical College ＆ Chinese Academy of Medical Sciences, Beijing 100050 |
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| 摘 要： | It was well known that furostan saponin was a kind of natural products with a broadrange of promising pharmaceutical properities1. Structurally, furostan saponins usuallyhave bidesmosidic sugar moieties substituted at 3-OH and 26-OH position2. However,fur…
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| 关 键 词： | 全合成 呋甾烷皂角苷 糖基化 icogenin glycosylation |
| 收稿时间： | 2005-06-27 |
Total Synthesis of the Analogue of Icogenin |
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| Shu Jie HOU Peng XU Liang ZHOU De Quan YU Ping Sheng LEI Chuan Chun ZOU.Total Synthesis of the Analogue of Icogenin[J].Chinese Chemical Letters,2006,17(2):183-186. |
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| Authors: | Shu Jie HOU Peng XU Liang ZHOU De Quan YU Ping Sheng LEI Chuan Chun ZOU |
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| Institution: | Peking Union Medical College |
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| Abstract: | One of the analogues of icogenin, a natural furostanol saponin showing strong cytotoxiceffect on cancer cell, was first synthesized via convergent strategy by using diosgenin and availablemonosaccharides as starting materials, |
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| Keywords: | Furostan saponin icogenin glycosylation kyptogenin |
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