Alkylation of 2-(hydroxyimino)-5H-[1,3]thiazolo[3,2-a]-pyrimidin-3(2H)-ones |
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Authors: | E. A. Lashmanova V. S. Larina A. K. Shiryaev |
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Affiliation: | 1.Samara State Technical University,Samara,Russia |
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Abstract: | Alkylation products were obtained from ethyl 2-(hydroxyimino)-7-methyl-3-oxo-5-aryl-2,3- dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidin-6-carboxylates at the treatment with alkyl halides, dimethyl sulfate, and diazomethane. Diazomethane alkylated the initial substrate at the oxygen atom of the carbonyl group of the thiazolidine fragment, the other reagents, at the oxygen atom of the hydroxyimino group. |
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