Synthesis of 2-(3,4,5-trimethoxybenzoyl)-4(5)-phenyl-1<Emphasis Type="Italic">H</Emphasis>-imidazole |
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| Authors: | E B Nikolaenkova I A Os’kina A Ya Tikhonov |
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| Institution: | 1.Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch,Russian Academy of Sciences,Novosibirsk,Russia |
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| Abstract: | The condensation of (2E)-N-hydroxy-2-hydroxyimino-2-phenylethanamine with 3,4,5-trimethoxyphenylglyoxal afforded (1-hydroxy-5-phenyl-1H-imidazol-2-yl)phenylmethanone which reacted with trimethyl phosphite or chloroacetone to give 2-(3,4,5-trimethoxybenzoyl)-4(5)-phenyl-1H-imidazole. |
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