Synthesis of 7-(2-R-pyrimidin-4-yl)- and 7-(2-R-[1,2,4]triazolo[1,5-<Emphasis Type="Italic">a</Emphasis>]pyrimidin-7-yl)-2,2,4,6-tetramethyl-1,2,3,4-tetrahydroquinolines |
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| Authors: | A Yu Potapov Kh S Shikhaliev M A Potapov M A Prezent D Yu Vandyshev |
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| Institution: | 1.Voronezh State University,Voronezh,Russia;2.Zelinskii Institute of Organic Chemistry,Russian Academy of Sciences,Moscow,Russia |
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| Abstract: | Cyclization of 3-(dimethylamino)-1-(2,2,4,6-tetramethyl-1,2,3,4-tetrahydroquinolin-7-yl)prop-2-en-1-one with carboximidamides, guanidines, and 1,2,4-triazol-5-amines afforded a number of new 2,2,4,6-tetramethyl-7-(2-R-pyrimidin-4-yl)-1,2,3,4-tetrahydroquinolines and 2,2,4,6-tetramethyl-7-(2-R-1,2,4]triazolo-1,5-a]pyrimidin-7-yl)-1,2,3,4-tetrahydroquinolines. |
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