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Green procedure for the synthesis of 1,4-dihydropyrano[2,3-<Emphasis Type="Italic">c</Emphasis>]pyrazoles using saccharose
Authors:Mehrnoosh?Kangani  Email author" target="_blank">Nourallah?HazeriEmail author  Malek?Taher?Maghsoodlou  Khatereh?Khandan-Barani  Maryam?Kheyrollahi  Fereshteh?Nezhadshahrokhabadi
Institution:1.Department of Chemistry,University of Sistan and Baluchestan,Zahedan,Iran;2.Department of Chemistry,Azad University, Branch of Zahedan,Zahedan,Iran
Abstract:Saccharose was applied as an efficient and homogeneous catalyst for one-pot, four-component synthesis of 1,4-dihydropyrano2,3-c]pyrazole derivatives from aromatic aldehydes, malononitrile, ethyl acetoacetate and hydrazine monohydrate under thermal solvent-free conditions. This protocol has a considerable number of advantages including mild condition, high yields, operational simplicity, environmentally benign and simple work-up procedures.
Keywords:
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