PEG-Chitosan as a Perspective Stabilizing Agent for Liposomal Suspensions: The Influence of the Molecular Weight and Degree of PEGylation on the Physicochemical Properties of the Complex期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

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PEG-Chitosan as a Perspective Stabilizing Agent for Liposomal Suspensions: The Influence of the Molecular Weight and Degree of PEGylation on the Physicochemical Properties of the Complex

Authors:	Email author" target="_blank">I?M?Le-Deygen Email author E?V?Kudryashova

Institution:	1.Department of Chemistry,Moscow State University,Moscow,Russia

Abstract:	The possibility of regulating the physicochemical properties (stability, size, and binding sites) of liposomal containers for drug delivery by selecting the molecular weight and degree of modification of PEG-chitosan is demonstrated. The effect of the regulation of the release of doxorubicin from liposomal containers depending on the properties of the polymer and pH is demonstrated.

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