| 正交试验设计在麦白霉素高产菌株选育中的应用 |
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| 引用本文： | 康宗贤 李建正. 正交试验设计在麦白霉素高产菌株选育中的应用[J]. 数理统计与管理, 1994, 13(5): 24-27 |
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| 作者姓名： | 康宗贤 李建正 |
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| 作者单位： | 开封医学高等专科学校，河南医药工业研究所 |
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| 摘 要： | 本文应用正交试验设计改进了麦白霉素的生产工艺，在四个关键环节上选出了比对照组高出７００μ／ｍｌ以上的高产稳定菌株。该法使试验次数减少，选育周期缩短，既节省了人力物力和降低了生产成本，又增加了麦白霉素药粉的产量，取得了可观的经济效益。
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| 关 键 词： | 正交试验设计；麦白霉素；菌株 |
The Application of Experiment Design of Orthogonal Array to the Selection of High-yield Strains of Meleumycin |
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| Tang Zong-xian, Wang Hua-he, Yang Bao-hua. The Application of Experiment Design of Orthogonal Array to the Selection of High-yield Strains of Meleumycin[J]. Application of Statistics and Management, 1994, 13(5): 24-27 |
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| Authors: | Tang Zong-xian Wang Hua-he Yang Bao-hua |
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| Affiliation: | Tang Zong-xian; Wang Hua-he; Yang Bao-hua(Kaifeng Medical College 475001)Li Jian-zheng(Henan Industry Institute of Medical & Pharme -ceutical 475003) |
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| Abstract: | In this paper we apply the experiment design of orthogonal array to improve the procedure of meleumycin production. After it has been used in the four key links in the production chain, the high-yield and stable strain of meleumycin is selscted, which is over 700μ/mlhigher than that of the contrast group. This design makes the experiment frequency reduced and the cycle of selection shortened, thus not only using manpower and material resources sparingly and reducing the production cost, but also increasing the output of meleumycin powder. In so doing, considerable economic profit should be gained. |
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| Keywords: | Orthogonal array Experiment design Meleumycin Strain |
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