Total synthesis of amphidinolide J |
| |
| Authors: | Barbazanges Marion Meyer Christophe Cossy Janine |
| |
| Institution: | Laboratoire de Chimie Organique, ESPCI ParisTech, CNRS, 10 rue Vauquelin, 75231 Paris Cedex 05, France. |
| |
| Abstract: | The marine natural product amphidinolide J has been synthesized according to a convergent strategy. The key steps of this synthesis include a B-alkyl Suzuki-Miyaura coupling and the addition of an alkynyllithium reagent to a Weinreb amide to build the C4-C5 and C12-C13 bonds, respectively, and a Yamaguchi macrolactonization. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
