| QCM Detection of Adhesion, Spreading and Proliferation of Human Breast Cancer Cells （MCF-7） on a Gold Surface |
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| 作者姓名： | Xue En JIA Zhi Wei ZHANG Liang TAN You Yu ZHANG Qing Ji XIE Zhi Min HE Shou Zhuo YAO |
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| 作者单位： | [1]Key Laboratory of Chemical Biology ＆ Traditional Chinese Medicine Research （Ministry of Education）, College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410081 [2]Cancer Research Institute, Xiangya Medical College, Central South University, Changsha 410078 |
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| 基金项目： | 中国科学院资助项目;科技部专项基金;教育部科学技术研究项目 |
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| 摘 要： | The quartz crystal microbalance (QCM) was used to monitor the one-day incubation of human breast cancer cells (MCF-7) on the gold electrode. In combination with an optical microscope simulation experiment, the cell-population pictures at various stages, the QCM responses to the cells' adhesion, spreading and proliferation on the electrode surface were discussed. The △f0 and △R1 responses were found mainly from mixed effects of viscodensity and surface stress, and in proportion to the cell coverage, rather than to the number of cells at the electrode. The significant fore-and-aft changes in cyclic voltammetry and electrochemical impedance spectroscopy of the ferri-ferrocyanide redox couple also proved that the cells were adhesion to the gold surface.
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| 关 键 词： | 石英晶体微量天平 光学显微镜方法 循环伏安法 电气化学阻抗光谱学 乳癌 癌细胞 |
| 收稿时间： | 2005-09-08 |
QCM Detection of Adhesion, Spreading and Proliferation of Human Breast Cancer Cells (MCF-7) on a Gold Surface |
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| Xue En JIA Zhi Wei ZHANG Liang TAN You Yu ZHANG Qing Ji XIE Zhi Min HE Shou Zhuo YAO.QCM Detection of Adhesion, Spreading and Proliferation of Human Breast Cancer Cells (MCF-7) on a Gold Surface[J].Chinese Chemical Letters,2006,17(4):509-512. |
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| Authors: | Xue En JIA Zhi Wei ZHANG Liang TAN You Yu ZHANG Qing Ji XIE Zhi Min HE Shou Zhuo YAO |
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| Institution: | Ministry of Education |
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| Abstract: | |
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| Keywords: | Quartz crystal microbalance optical microscopy cyclic voltammetry electrochemical impedance spectroscopy human breast cancer cells (MCF-7) |
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