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Alkyne Aminopalladation/Heck and Suzuki Cascades: An Approach to Tetrasubstituted Enamines |
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| Authors: | Finn J. Geffers Florens R. Kurth Prof. Dr. Peter G. Jones Prof. Dr. Daniel B. Werz |
| Affiliation: | 1. Technische Universität Braunschweig, Institute of Organic Chemistry, Hagenring 30, 38106 Braunschweig, Germany;2. Technische Universität Braunschweig, Institute of Inorganic and Analytical Chemistry, Hagenring 30, 38106 Braunschweig, Germany |
| Abstract: | Alkyne aminopalladation reactions starting from tosylamides are reported. The emerging vinylic Pd species are converted either in an intramolecular Heck reaction with olefinic units or in an intermolecular Suzuki reaction by using boronic acids exhibiting broad functional group tolerance. Tetra(hetero)substituted tosylated enamines are obtained in a simple one-pot process. |
| Keywords: | alkynes carboamination cascades Pd catalysis tetrasubstituted olefins |