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Fluorescence Emission of Self-assembling Amyloid-like Peptides: Solution versus Solid State |
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| Authors: | Dr Carlo Diaferia Dr Chiara Schiattarella Dr Enrico Gallo Dr Bartolomeo Della Ventura Prof Giancarlo Morelli Prof Raffaele Velotta Dr Luigi Vitagliano Prof Antonella Accardo |
| Institution: | 1. Department of Pharmacy and, Research Centre on Bioactive Peptides (CIRPeB), University of Naples “Federico II”, Via Mezzocannone 16, Naples, 80134 Italy;2. Institute of Applied Sciences and Intelligent Systems, CNR, Via P. Castellino 111, Naples, 80131 Italy;3. IRCCS SDN, Via Gianturco 113, Naples, 80143 Italy;4. Department of Physics “Ettore Pancini”, University of Naples “Federico II”, Via Cintia 26, Naples, 80125 Italy;5. Institute of Biostructures and Bioimaging (IBB), CNR, Via Mezzocannone 16, 80134 Naples, Italy |
| Abstract: | Analysis of the intrinsic UV-visible fluorescence exhibited by self-assembling amyloid-like peptides in solution and in solid the state highlights that their physical state has a profound impact on the optical properties. In the solid state, a linear dependence of the fluorescence emission peaks as a function of excitation wavelength is detected. On the contrary, an excitation-independent emission is observed in solution. The present findings constitute a valuable benchmark for current and future explanations of the fluorescence emission by amyloids. |
| Keywords: | amyloid fluorescence intrinsic fluorescence peptide materials self-assembly solid state |