Facile synthesis of highly functionalized stable ketenimines by a three-component reaction of alkyl isocyanides, dialkyl acetylenedicarboxylates and ethyl carbazones |
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| Authors: | Mohammad Anary-Abbasinejad Hossein Anaraki-Ardakani Fatemeh Ghanea |
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| Affiliation: | (1) Department of Chemistry, Islamic Azad University, Yazd Branch, Yazd, Iran |
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| Abstract: | Abstract The reactive intermediate generated by the reaction of alkyl isocyanides and dialkyl acetylenedicarboxylates was trapped by ethyl carbazones to produce stable ketenimine derivatives in good yield. The reaction is characterized by mild conditions, high selectivity, and tolerance to various functional groups. Graphical abstract  |
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| Keywords: | Isocyanides Ethyl carbazones Ketenimines Multicomponent reactions Acetylenic esters |
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