Spectrophotometric and polarographic investigation of the Ofloxacin-Cu(II) complexes |
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| Authors: | Kapetanović V Milovanović L Erceg M |
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| Affiliation: | Faculty of Pharmacy, University of Belgrade, Belgrade, Yugoslavia |
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| Abstract: | By means of spectrophotometric methods it was found that ofloxacin reacts with copper(II) ions to form complexes with molar ratios of ofloxacin: Cu(II) of 1:1 at pH 4.00, 2:1 at pH 7.02 and 3:1 at pH 8.30. The stability constants of the complexes were determined. The formation of ofloxacin:Cu(II) 1:1 and 3:1 complexes was confirmed by a polarographic method and the corresponding overall stability constant was evaluated. |
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| Keywords: | Cu(II)-Ofloxacin complexes Polarography Spectrophotometry Stability constants |
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