New benzylpiperazine derivatives bearing mono‐ and bis‐dialkyl substituted 1,2,4‐triazoles |
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Authors: | Yaseen A Al‐Soud Mohammed N A Qalalweh Haitham H Al‐Sa'doni Najim A Al‐Masoudi |
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Abstract: | Cycloaddition of the 1‐aza‐2‐azoniaallenes 3 with p‐cyanobenzyl chlorides afforded, after spontaneous rearrangement, the 1,5‐dialkyl‐3‐4‐chloromethyl)phenyl]‐1H‐1,2,4]‐triazoles 6 . A series of 1,5‐dialkyl‐1H‐1,2,4]‐triazol‐3‐yl)benzyl‐piperazines 7 and 8 were prepared from direct condensation of 6 with piperazine and N‐methylpiperazine, respectively. The structures of the newly synthesized products were identified by 2D NMR spectroscopy. © 2005 Wiley Periodicals, Inc. Heteroatom Chem 16:28–32, 2005; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20061 |
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