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Stereoselective Synthesis of Isomers of the Naturally Occurring 13-Hydroxy-2,4,9-tetradecatrienoic Acid. Part II [1]
Authors:Antje?Huefner  author-information"  >  author-information__contact u-icon-before"  >  mailto:antje.huefner@uni-graz.at"   title="  antje.huefner@uni-graz.at"   itemprop="  email"   data-track="  click"   data-track-action="  Email author"   data-track-label="  "  >Email author,Christa?Hoeller,Gottfried?Reznicek
Affiliation:(1) Institute of Pharmaceutical Chemistry and Pharmaceutical Technology, University of Graz, A-8010 Graz, Austria;(2) Institute of Pharmacognosy, University of Vienna, PharmaCenter Vienna, A-1090 Wien, Austria
Abstract:Summary. The stereoselective syntheses of four unsaturated hydroxy fatty acids 13S,2E,4E,9E)- 13-hydroxy-2,4,9-tetradecatrienoic acid, (13S,9Z,11E)-13-hydroxy-9,11-tetradecadienoic acid, (13S,9E, 11E)-13-hydroxy-9,11-tetradecadienoic acid, and (13S,2E,4E,9E)-13-hydroxy-2,4,9,11-tetradecatrienoic acid, are described. Wittig reactions, regioselective oxidation of dialcohol 3, and diastereomerization were used.
Keywords:. Fatty acid   Aldehydes   Wittig Reaction   (Z,E)-Isomerization.
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