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Synthesis of 2- and 3-pyridinyl(aryl)methanones
Authors:Popova  I. S.  Formanovsky  A. A.  Mikhura  I. V.
Affiliation:(1) Russian Academy of Sciences, M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, 16/10 ul. Miklukho-Maklaya, 117997 Moscow, Russian Federation
Abstract:A procedure was developed for the preparation of 2- and 3-pyridinyl(aryl)methanones by the reactions of aryllithium with methyl pyridinecarboxylate and methyl esters of substituted phenylcarboxylic acids.
Keywords:aryl(pyridinyl)methanones  2-pyridinyllithium  3-pyridinyllithium  4-methoxyphenyllithium  acylation
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