Configurational assignment of rhizopodin, an actin-binding macrolide from the myxobacterium Myxococcus stipitatus |
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| Authors: | Horstmann Nicole Menche Dirk |
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| Institution: | Helmholtz-Zentrum für Infektionsforschung GmbH, Medizinische Chemie, Inhoffenstr. 7, 38124 Braunschweig, Germany, EU. |
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| Abstract: | The relative and absolute stereochemistry of the 38-membered myxobacterial polyketide rhizopodin, a potent actin-binding macrolide, was determined by J-based configurational analysis in combination with molecular modeling and chemical derivatization. |
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